Disorders of Erythrocyte Function|Essay guru
Posted: January 30th, 2023
1.Sickle cell disease is an adaptive response against malaria. Discuss and identify the pathogen and transmission of malaria.
2. Where and why do you think an adaptation occurred that led to the development of sickle cell disease and what is the pathophysiology of the adaptation?
3. Why do people who no longer live in parts of the world where malaria is prevalent still develop sickle cell disease and how and why does it occur?
4.How can we advise families with this debilitating disease?
RUBRIC
1. Resources are to be sited. If it is not your original thought or idea you must give credit to the author, if not sited it is considered plagiarism.
2. Resources are not to be older than 5 years old and it must be scholarly peer reviewed journals!
3. All written material must be in APA format. Please use the latest manual. Points will be deducted as per rubic if not done correctly.
4. Please expand your ideas and add your thought to your writing. Why did you use that resources? What will this quote add to the discussion?
You are now at the master’s level, you can agree or disagree with the author. Your opinion and experience counts!
must be at least 1 and half page long
SOLUTION
- Malaria is caused by the parasite Plasmodium, which is transmitted through the bite of infected female Anopheles mosquitoes.
- Sickle cell disease is thought to have evolved as an adaptive response to malaria because individuals with the sickle cell trait (a single copy of the gene) have some resistance to severe malaria infections. This adaptation likely occurred in regions of the world where malaria is prevalent, such as Sub-Saharan Africa. The pathophysiology of the adaptation is that the sickle-shaped red blood cells caused by the sickle cell gene are less susceptible to being infected and destroyed by the Plasmodium parasite, thus reducing the severity of malaria.
- Despite no longer living in areas where malaria is prevalent, people with African ancestry may still carry the sickle cell gene due to historical migration patterns and cultural practices that promote gene retention. Sickle cell disease occurs in these individuals when they inherit two copies of the sickle cell gene, one from each parent.
- Families with sickle cell disease can be advised to:
- Seek medical care regularly to manage symptoms and prevent complications
- Eat a balanced and nutritious diet
- Maintain regular physical activity and hydration
- Avoid infection through frequent hand washing and vaccination
- Learn about their condition and participate in treatment decisions
- Connect with support groups and counseling services for emotional support.
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