The replication process of SARs-COV-2, describing the different steps involved|My homework helper

Posted: February 10th, 2023

https://media.hhmi.org/biointeractive/click/covid/

The above link has four-part animation series that explores the biology of the virus, including the structure of coronaviruses like SARS-CoV-2, how they infect humans and replicate inside cells, how the viruses evolve, methods used to detect active and past SARS-CoV-2 infections, and how different types of vaccinations for SARS-CoV-2 prevent disease.

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After watching all parts of the animation,

Discuss any two of the following 4 prompts

  1. The replication process of SARs-COV-2, describing the different steps involved.
  2. How mutations arise in viral genome and how it changes the virus over time.
  3. Discuss the different ways to detect viral infection
  4. Discuss the how different types of vaccines trigger an immune response

Also include a short paragraph on

  • Did this animation help to correct any misconceptions you had about SARS CoV-2 or Covid-19?

SOLUTION

The replication process of SARS-CoV-2 (the virus that causes COVID-19) involves several steps:

  1. Attachment: The virus attaches to the ACE2 receptor on human cells.
  2. Entry: The virus enters the human cell and releases its genetic material into the cell.
  3. Replication: The virus’s genetic material, RNA, is used as a template to produce new viral RNA and proteins.
  4. Assembly: The newly produced viral proteins and RNA come together to form new viruses.
  5. Release: The new viruses leave the human cell and infect other cells.

Mutations can arise in the viral genome due to errors in the replication process. These mutations can cause changes in the virus, such as changes in its surface proteins. Over time, these changes can accumulate, leading to the evolution of the virus.

There are several ways to detect a viral infection, including:

  1. PCR (Polymerase Chain Reaction): This test detects the presence of the virus’s genetic material in a sample taken from the patient.
  2. Antigen tests: These tests detect viral proteins on the surface of the virus.
  3. Antibody tests: These tests detect antibodies produced by the body in response to the virus.

Different types of vaccines trigger an immune response in different ways. For example:

  1. Inactivated or killed vaccines: These vaccines contain dead or inactivated virus particles that cannot cause disease. The immune system recognizes these particles and produces an immune response.
  2. Live attenuated vaccines: These vaccines contain weakened virus particles that can cause a mild infection. The immune system recognizes the weakened virus and produces an immune response.
  3. Recombinant vaccines: These vaccines contain pieces of the virus’s genetic material that are produced in a laboratory. The immune system recognizes these viral proteins

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