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Posted: December 15th, 2023

question 1) 1 page max plus scheme
For miR-27, miR-33, miR-124 and Let7 answer the following questions:
What are the gulde strand sequences of the mature miRNA?
What are the seed sequences?
Proposal a mutant miRNA seed sequence to use as a control in testing for miRNA binding.
Question2) 2 pages max plus scheme Draw your own version of the exosome biogenesis pathway that includes endogenously synthesized proteins on the ER and endogenously produced microRNAs produced in mature form in the cytoplasm.
How do researchers show that extracellular vesicles are exosomes?